Elevated Kappa Light Chains In Urine

These tests are used as an aid in the diagnosis and monitoring of multiple myeloma and related disorders.

Elevated kappa light chains in urine.

Leclair provides a thorough scientific breakdown of light chains and the way they work. Thank you for putting things in simple terms and also for the deciphering my myeloma lab results which i printed out. There are two types of immunoglobulin light chain produced in humans. Light chains molecular weight 22 000 d are polypeptides that are synthesized by plasma cells and form part of immunoglobulins.

Immunoglobulin light chains that are circulating in serum in a free unbound state are called free light chains flcs measurement of the serum level of flcs became practical as a clinical blood test in recent decades. Plasma cells normally produce a slight excess of light chains that are either excreted or catabolized by the kidney and only a minute amount of light chain protein normally appears in the urine. Increased kappa free light chains and an increased kappa lambda ratio may be seen with plasma cell disorders that produce excess monoclonal kappa light chains. What else should i ask answered by dr.

She told me not to worry and we ll check again in 3 months. In this patient power segment host dr. I guess we are going on a journey and i pray he will come out on the other side. Told me my kappa light chain is elevated at 26.

Your article has helped me to understand what this means. Leclair is a patient power host and retired. Free light chains will normally be present in the blood at low levels with a kappa lambda ratio of approximately 0 26 to 1 65 for individuals with normal kidney function. In the clip dr.

You have a minimal degree of change this may be wi. His kappa light chain free serum level is high.